"The first trick of asking questions is to determine if your question is a good one. Just because a question has never been asked does not make it a good one. Smart people have been asking questions for quite a few centuries now, so many of the questions that haven't been asked are bound to yield uninteresting answers.
"But if you can question something that people really care about and find an answer that may surprise them--that is, if you can overturn the conventional wisdom--then you may have some luck." (p. 89)